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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2180e4fd466ea521a0f6b28714b697a4ca397af127ab1b19a1ed23fd5cb1b96f' 
  AND token = 'jYDPkTIK9ihMq5V7LcQUDxri6rX1oJoIeUu30BKZcDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}