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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '174afc3953707c1867b4c73f75b7ec131025b80887ffebd5c31d920233b2df8d' 
  AND token = 'Jc7EixyVSSndXPIzm1FC9IJ5NWv7geTzYG0LG/Grft8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}