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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85916fe95c1517120af992916dac78e97615af83d5a9d67d3fc2b837d0d2f49d' 
  AND token = 'nLgO6Yegay7ozdRAd/qlyD6relLBNLYCSgZDreL7M9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}