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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c850f3983f1e8d8e7b15fdad0ad9cd9a4d7c0f602b5e87bdfd6b332d6724436' 
  AND token = 'XSNx9c+G7AuU1kypo0x8DX/eiruq+FAQpZqxFlhgwpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}