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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a472035cf2eeaa9450bfa2a01d581bed8b04b15923aa0b9926e6a5d35dd91e' 
  AND token = '4N93AMMkV2iNYZ0RpFu/+6p8xh2LivpEdzg7a0T+D78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}