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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c441bcc7ebe9ec135c72f96648584e52b0a6057526d88b86687781748e233c' 
  AND token = 'B1TZ9c/lm82xu5uIT8JFXfEU/uh/W/Tr1d6fTh47ZtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}