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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d5a2b5a825f6a60b1c821995dc9ee6df9352cec62254f96f300c4976f2956be' 
  AND token = 'edGND2lX9GpW2EhAsmBAri4L6uh32r/qvdJ7Dzuv2Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}