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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1c5579acbc5be1f5ef733e77062a470d0795fcf4df11c1d0d252d176de41034' 
  AND token = 'i4tJPzPAPLqNjbOQM4o7xr2K3HdWp2HeB2dwdl6c1Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}