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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dffb3d1e1b965b9c4371629d389a107b56c5ba200bb6c79c15ac07afa4801552' 
  AND token = 'yJoMCW3dOOICLcr/FQBvEStk+Kv3u+TSg2lWQj0yaE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}