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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ebc67148008679f4b40220851218707849f9eeefd9063d35f9c29f992e4be82' 
  AND token = 'nR29WX2zCxm/KGOS1LygfNxssR/1jLoVFXJhw5oOYrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}