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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7b4c5647bb7c13decddeea0f649dafb60e5ad28a9b998bdaa67d0731781e6c0' 
  AND token = 'nj1tPIOc3pYxfwiveiZT0zVzcsfVE5L3WQT3WLTDOVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}