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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25872f236bb5e295d245365fa8c00dd4b3486200425a395bc7381199696f57dc' 
  AND token = 'gt+aRYzQc0Nf5mFUR4OpZ6eCkTheFfbAfvgSQXJo3Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}