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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e41952a30a01d420fe0cc4d3c64adf11228347ef1621f5feada687ca64ab3591' 
  AND token = 'F275LtuhvolBe9mk/vjfT1aNo4zCcuVTi4uxR9HWCSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}