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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89b043aa2b3f15601c4a8f1ab2872da1c677857c455599523da9ada4b5c826f4' 
  AND token = 'Q/gXjmNAjRJID4iOSAHSDIQp5+HLQbr1Az7uHrG6SYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}