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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd51ab14cd326057de77f9da0affa4a7f1fc9c034084c555eea2212550b323311' 
  AND token = 'GuE6T+Wj1mV/RLtBQ85Qn4sc3kSmcI39mH0plm6whbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}