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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6353726877220332efac831af2c4a5f76f207f27c082fd63c0e205ccced5a560' 
  AND token = 'gBj+zilnKEVLbrthaJCQlKC1LpSRNtSBDM28/weMpGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}