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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e277292a845b2fbd5b0ce7c0c55fe103f282e76487a8881ec80ee1e92ee66ef' 
  AND token = 'TNclR+cAGTQUk2F/uhg2V22fqj5JOR/fCEsGp7JMmRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}