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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4848af39348d7bdf71a028a2edb3ebb3a428c59b7a11d1ce4958c26516403863' 
  AND token = '0XxWLoXmBrw7Htuh9ki2L2pHYsuLXqaP0K87XnrL2rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}