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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6378888513074d1e630506da07c9c8187d17cd8206324bd557706f9b5d5439ac' 
  AND token = 'qtV3FJKEkYUHycOGEGe15hj3Apdb/sylI+g7WBqb4r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}