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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb6dd0d46696cdd056799fad5ae9a5401fd084b94aad5728aed19287f2c47269' 
  AND token = 'SpAp0T4hFCbIANeXhB5c/zoiE7Hcp3YVTHBZP3HBemc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}