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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f5c6e931aa4fe7aa6ed2bb92fd40987d2f241f60e123fa09a00332ee073326d' 
  AND token = 'Mr9qnYOK0GrD9CCyZ+M1ati0E25nBDAGAWCjkfA7sys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}