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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02c8f249dfa35b014bd2a82c26f72fee2cf0a35d5c8fafe00801c355f5b8a36b' 
  AND token = 'R2kxhOFa+684uHYDJ0KWxj+FCKiDYi/H6qfHs9/VfpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}