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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce2009604feba5002531d0a19796227860f6308bd4c5feb351628da2a58fa72' 
  AND token = '6M45CkysT71otwNJfCzItM4iJoURxcijJdPb2KT13ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}