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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c0e42d306de9e117fce50804e91672886ad1d399c9bdb521dbafa8d26e32673' 
  AND token = 'YG9nTMbpgrbc7583nDqCiPlz9f1TlRmA5iNMhhRT8Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}