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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65dbafc0a8173b6b3bfbd1d56a9b834127efbea4af8228e86c3f330e80f484b7' 
  AND token = 'v4dxfz/NTpxJqR3AJ6FuBe1ieiSM84GVnWtkvyETw9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}