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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65e3e482082dc78b9057dbcb4370cf7a921e5d1d705f0319054c66336270909' 
  AND token = 'f+mU7QzwyqSER0GGXa0BrLijQfwHL9R2rl7iToNqzfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}