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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abfd88567f82310b9a6654d4ff3976800c9e6964095111648337029116699f3f' 
  AND token = 'HWHTlPoNimzupKTZiz4XQiU4k9xnl2W2jFl2YR+tpMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}