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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89df66f75f4597f816b25d9ec9878a989f18d45d5c3c2a0d0e14c6270d95f447' 
  AND token = 'P3/uYbsGWqmhf87UTdpohPcOFWAqJmIi0klp0cD1Tzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}