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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbfe3bbda5f5fa7539bd736f3264a12b3e18fa180bd074637a52cb8c646d9a62' 
  AND token = 'opRENltg1zUDCMMvCkPN3u/BZ7PELLDSTxK8NDzAebE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}