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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1641c81fb604eeed325e5e05169a27484e518e47b0e4575d5a20d1648908d8c5' 
  AND token = 'U42fdRCybKqFm7Lv+AZPqYW40dDCTR7yROtuPcd0l/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}