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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ad34cc892ad9501adcb7482052604c2cc02e8697dbfff6127fdd15e3c327d10' 
  AND token = 'dAhJSUQqQnWy9bkoPNcfWPLYOJyhBw1hK5uXiSixqJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00121

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}