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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2385d2f157a49c495b07fac454673618b286a6275e0b3fe9291760e40b16fd46' 
  AND token = 'YTNJYO6jLMhG9YiHas2tHTl+rGbM/JVO6rNCAot4bIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}