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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5597ac648707e2b65eb3d5205808dbdfeac8f647e34ee4288f515b0b39256888' 
  AND token = 'w99muwZV9W+YIecbOdRvcZOtBk1gTWZc7P7zGBX7uz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}