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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4282d577e03d1cc3eea25e4c5ae07aab7e6459da17d974498f678c73e9c6b85a' 
  AND token = 'VFR0qq+G75uenZhoeFeDHlcygDv4V9WLxgU4qgeRiJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}