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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8fa5fa10d38192d8196a19122b7e58402e127014245534db521df31e3b2f01' 
  AND token = 'lEz0f1HvYubb6pTXlx6W0hwxSxzRsYar1iNUo044Ymw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}