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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a00c145281a83ba8aae02898b29007311faadb7d80be93567de97b12531fa0f' 
  AND token = '0qVZGmPiCfceFKYWU1v0x1foG7QD/FFtBZepT/drrQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}