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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4b38cd371bb81732707a593d80266a3d77d4ef5f69beb37c14c0e6b81dd003' 
  AND token = 'VqoulmBYioomZ+iZq75rk4WmoiBtXg4BMA9r80HHPhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}