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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3ccb0965a3c91af2bc518dad6501fd7a4dac5d0a1fc0509b4e87c9afff0278' 
  AND token = '2KicJa551gXdQ9G3FSp2D/Hszv2aXX3fJSZpJ5Cwpu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}