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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6643a2c2abb6024af4d28c81cbb44135a2fbac42972e95df473a566dfefb5ad0' 
  AND token = '3uK8CO5VvUKUCkl3NDzii7nl6fNwhb/TsRCXACttNE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}