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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd889d8c239a225e0b1ee7e262e522fb4022fbb2dc41ec355beb50f02499154cc' 
  AND token = 'CgYHmm67rDKn5q3tPBb+NqIPYaJmeGEuPTwnaQSEO1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}