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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38a78d91e8ebcdc9b079a30e90950f9c84f96c445751dcda15775c78d5ab42c8' 
  AND token = 'eHYoN8Nd3Z1MMVDm/LEzuCqtEvnlJj7OdfEAiJknOQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}