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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9fe9e45ff09190f1415b6a59244842fc9975155b4d3b1d355f50d020f943f4' 
  AND token = 'VNT6vztntcD/YvN3/W4JIdWdL5cNnvhtnqSW1IijOLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}