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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4dac49c4e10f1de69172921056fec21c7390d022f93da597bafb67161fb2fc0' 
  AND token = 'js2R2b7d+7O1EyswmrMeJ8i34vo4g7rY+FOFJqsT0hU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}