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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0f4b69270c6a7ce3e71a1da20b8745bd13608f04b7bf38951ae180256f4af4b' 
  AND token = 'QNE2H4RxpIwRtd/lAhzhgH5UJRk/OT1Na0d+xriWxrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}