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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b44900841371c98a227add9fe3fdaf0fb4715292283a6b24266514f490d1010' 
  AND token = '0EuE9VfF1ipvwq0SaoOPvT3JuzlZ0aRqubPdjX3diGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}