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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c45d98c9a7b877ada089f8a2ded865a7c714ff87bf8418a0f37b7386d7bf3598' 
  AND token = 'UIgQHVc/2E9qR/3nShDf+p6TI41viThMwYTgT8dRmKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}