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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781345e826503f27bc76fe32982c8b967b57bc29190ea6dcfec15287732f6dc5' 
  AND token = 'r6xPaYGSnX0I9UK3xvBtWF5cROP21/qmm87tc3dSRUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}