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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c039a792c476eda109d4c842e07f1b66761f32951a5a31e65b476138eddaf2a8' 
  AND token = 'tL9YFPf6fItHYm+rXoS28Prjj3A+i3BvZDUTS8M2Ryg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}