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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265c42806961e354d247b705a30c2cdd0a8f04d185b89b0ed593c1c2902f0b81' 
  AND token = 'FtayB8QqSgys36xbvp8d5VZQulQU1DmuQuwiJLgWLQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}