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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49009e2024f0b7f4164e31483a0f0eb9cc8f5d96597826f33cefc5162180959f' 
  AND token = 'IfP1wxkY703pN6xyFnK/YBnzcVrZAe6sBLR5J87DnwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}